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Why Sandra Day O'Connor's dementia progression might be slow

Sandra Day O'Connor shares dementia diagnosis
Why dementia progression for Sandra Day O'Connor could be slow 04:09

Retired Supreme Court Justice Sandra Day O'Connor announced Tuesday she has been diagnosed with the early stages of dementia, possibly Alzheimer's. The 88-year-old, who was the first woman to sit on the U.S. Supreme Court, shared the news in a letter, saying she is no longer able to participate in public life.

"While the final chapter of my life with dementia may be trying, nothing has diminished my gratitude and deep appreciation for the countless blessings in my life," O'Connor wrote.

Alzheimer's affects 5.7 million people in the United States, according to the Alzheimer's Association, including about 10 percent of people over the age of 65.

Sandra Day O'Connor
Former U.S. Supreme Court Justice Sandra Day O'Connor Karen Bleier / AFP/Getty Images

While the diagnosis is certainly scary, the disease can manifest in many different ways depending on severity and a person's age of onset, explains Dr. Gayatri Devi, a neurologist at Lenox Hill Hospital in New York City who specializes in memory disorders.

"I think the thing that most of us worry about when we develop Alzheimer's which is more feared by older Americans than cancer, is that you're going to lose yourself," Devi said on "CBS This Morning" Wednesday.

However, for O'Connor, who is older and still has much of her cognitive reserve in her late 80s, Devi said she believes progression will be slow.

"The likelihood is very high that she's not going to lose herself," she said. "She's not going to lose her soul. She's going to continue to know who she is and the people around her until the end of her days."

Nearly two-thirds of those affected by Alzheimer's in the U.S. are women. This is due to a number of factors, Devi explained.

"First of all, women live longer so there are more women with Alzheimer's," she said. "Secondly, it seems as though women survive more with cerebrovascular disease of the brain compared to men who die earlier with it." Cerebrovascular disease, such as stroke or aneurysms, can impair normal brain function and predispose people to Alzheimer's disease.

Additionally, due to hormonal changes women are living much longer without the protective benefits of estrogen, which can increase risk.

While science has not yet established specific ways to prevent the progression of Alzheimer's disease, there are things doctors believe can help.

"Exercise, eat healthy, stimulate the parts of the brain that are failing. That helps because you don't lose [brain] plasticity just because you have Alzheimer's," Devi said.

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